Table 2.

Patient characteristics (mean ± SD unless otherwise noted).

CharacteristicsSLE, n = 149RA, n = 177
Demographics
  Age, yrs49.8 ± 9.758.5 ± 10.4
  White, n (%)130 (87)168 (95)
  Hypertension, n (%)78 (52)69 (39)
  Current smoker, n (%)16 (11)14 (8)
  Body mass index, kg/m227.6 ± 6.227.8 ± 5.8
  Waist circumference, cm85.6 ± 15.090.8 ± 16.3
  Hip circumference, cm101.6 ± 14.9105.5 ± 14.1
  Menopausal status, n (%)
    Pre/perimenopausal59 (40)35 (20)
    Postmenopausal77 (52)104 (59)
    Postmenopausal on estrogen13 (9)38 (21)
  College education, n (%)96 (64)99 (56)
Disease measures
  Disease duration, yrs16.5 ± 7.115.6 ± 10.6
  HAQ scoreNA0.75 ± 0.60
  Rheumatoid factor positivity, n (%)NA128 (74)
  SLEDAI, median (IQR)2 (0, 2)NA
  Renal involvement, n (%)36 (24)NA
Laboratory tests
  ESR, mm/h, median (IQR)10 (5, 20)10 (5, 25)
  CRP, mg/l, median (IQR) 2.35(0.94, 5.56)4.99 (1.76, 11.50)
  Creatinine, mg/dl0.87 ± 0.290.87 ± 0.25
  Albumin, mg/dl4.56 ± 0.503.96 ± 0.39
  HDL, mg/dl54.3 ± 16.661.1 ± 14.6
  LDL, mg/dl110 ± 34121 ± 34
  Tryglycerides, mg/dl, median (IQR)11 (76, 153)118 (88, 156)
  Total cholesterol, mg/dl190 ± 42209 ± 36
  Atherogenic ratio (total cholesterol/HDL)3.56 ± 0.863.74 ± 1.18
  Glucose ≥ 100 mg/dl, n (%)22 (15)19 (11)
  HOMA-IR > 2.114, n (%)95 (64)101 (57)
Current medications
  NSAID, n (%)57 (38)120 (68)
  Prednisone, n (%)
    0 mg/day92 (62)103 (59)
    > 0 – ≤ 2.5 mg/day6 (4)16 (9)
    > 2.5 – ≤ 5 mg/day9 (6)11 (6)
    > 5 mg/day42 (28)45 (26)
  HCQ, n (%)71 (48)31 (18)
  Nonbiologic DMARD, excluding
    HCQ, n (%)17 (11)84 (47)
  TNF inhibitors, n (%)NA55 (31)
  Immunosuppressants, n (%)26 (14)NA
  • SLE: systemic lupus erythematosus; RA: rheumatoid arthritis; HAQ: Health Assessment Questionnaire Disability Index; SLEDAI: Systemic Lupus Erythematosus Disease Activity Index; ESR: erythrocyte sedimentation rate; CRP: C-reactive protein; HDL: high-density lipoprotein; LDL: low-density lipoprotein; HOMA-IR: homeostasis model assessment-insulin; NSAID: nonsteroidal antiinflammatory drug; HCQ: hydroxychloroquine; DMARD: disease-modifying antirheumatic drug; TNF: tumor necrosis factor; IQR: interquartile range; NA: not applicable.