MID estimates for HAQ-DI, pain VAS, fatigue VAS, sleep VAS, and global VAS. Measures are mean (SD) [95% CI] change.
| Patient-rated Overall Status | HAQ-DI | Pain VAS | Fatigue VAS | Sleep VAS | Global VAS |
|---|---|---|---|---|---|
| Much better (n = 22) | −0.362 (0.432) [−0.554, −0.171] | −29.00 (31.86) [−43.13, −14.87] | −15.32 (22.54) [−25.31, −5.33] | −12.09 (28.57) [−24.76, 0.57] | −27.68 (30.43) [−41.17, −14.19] |
| Better (n = 35) | −0.131 (0.411) [−0.272, 0.0105] | −9.37 (24.37) [−17.74, −1.00] | −8.15 (23.52) [−16.35, 0.06] | −10.97 (29.74) [−21.35, −0.60] | −8.41 (21.17) [−15.80, −1.03] |
| Same (n = 89) | 0.00008 (0.292) [−0.0614, 0.0615] | −5.03 (20.37) [−9.45, −0.61] | −2.80 (20.89) [−7.33, 1.74] | 1.19 (22.89) [−3.72, 6.09] | −1.56 (15.73) [−4.93, 1.81] |
| Worse (n = 50) | 0.131 (0.309) [0.0436, 0.219] | 13.96 (22.05) [7.62, 20.29] | 3.63 (27.615) [−4.30, 11.56] | 13.81 (27.32) [5.88, 21.75] | 11.53 (21.03) [5.49, 17.57] |
| Much worse (n = 4) | 0.438 (0.315) [−0.0631, 0.938] | 16.50 (16.94) [−10.46, 43.46] | 27.50 (26.64) [−14.89, 69.89] | 4.75 (7.37) [−6.97, 16.47] | 20.75 (20.37) [−11.66, 53.16] |
| Spearman correlation coefficient* | 0.374 p < 0.01 | 0.448 p < 0.01 | 0.239 p < 0.01 | 0.326 p < 0.01 | 0.490 p < 0.01 |
↵* Correlation is between anchor and mean change in score, significant at the level shown. MID: minimally important difference; HAQ-DI: Health Assessment Questionnaire-Disability Index (0–3); VAS: visual analog scale (0–100 mm).