Table 2.

Medications in the 6 months prior to pregnancy and during pregnancy. P values are obtained from generalized estimating equations model, adjusting for repeated measures (using autoregressive correlation structure) for multiple pregnancies in the same mother.

MedicationNonrenal, n (%)Renal, n (%)p
Ever prior to the study period
  n11281
  Antihypertensive9 (13.4)10 (33.3)0.002
  Steroids76 (67.9)61 (75.3)0.53
  Antimalarials58 (51.8)30 (37.0)0.93
  Immunosuppressives19 (17.0)22 (27.2)0.11
In the 6 months pre-pregnancy
  n9269
  Antihypertensive5 (9.4)8 (28.6)0.002
  Steroids50 (54.4)48 (69.6)0.07
  Antimalarials34 (37.0)17 (24.6)0.85
  Immunosuppressives7 (7.6)13 (18.8)0.04
During pregnancy
  n9272
  Antihypertensive4 (7.4)7 (22.6)0.02
  Steroids59 (64.1)53 (73.6)0.43
  Antimalarials27 (29.4)19 (26.4)0.95
  Immunosuppressives1 (1.1)9 (12.5)0.02
Ever in study period
  n11281
  Antihypertensive7 (10.3)9 (27.3)0.001
  Steroids66 (58.9)61 (75.3)0.18
  Antimalarials41 (36.6)22 (27.2)0.72
  Immunosuppressives7 (6.3)14 (17.3)0.03