Univariate and multivariate regression analyses on predictors of pleuritis in SLE.
| Variable | Univariate OR (95% CI) | Multivariate 1† OR (95% CI) | Multivariate 2†† OR (95% CI) | Multivariate 3* OR (95% CI) |
|---|---|---|---|---|
| Age at SLE diagnosis ≤ 32 yrs vs > 32 yrs | 1.58 (1.19–2.10) | 1.52 (1.13–2.03) | 1.52 (1.14–2.04) | 1.38 (1.03–1.87) |
| Disease duration, ≥ 10 yrs vs < 10 yrs | 1.63 (1.23–2.16) | 1.33 (0.98–1.80) | 1.33 (0.98–1.82) | 1.39 (1.01–1.90) |
| SDI score | 1.16 (1.08–1.25) | 1.15 (1.13–2.03) | 1.15 (1.07–1.24) | 1.14(1.06–1.23) |
| Anti-Sm antibody | 1.40 (1.02–1.91) | — | 0.93 (0.62–1.41) | 1.29 (0.85–1.97) |
| Anti-RNP antibody | 1.57 (1.14–2.15) | 1.11 (0.74–1.65) | — | 1.10(0.72–1.70) |
| Concomitant RNP- and Sm-positive | 1.92 (1.31–2.82) | — | — | 1.98 (1.31–3.00) |
↵† Controlling for disease duration, SDI score, age at diagnosis, and anti-RNP-only-positive (n = 874);
↵†† controlling for disease duration, SDI score, age at diagnosis, and anti-Sm-only-positive (n = 874);
↵* controlling for disease duration, SDI score, age at diagnosis, anti-Sm-only-positive, anti-RNP-only-positive, concomitant Sm-and RNP-positive, concomitant Sm- and RNP-negative (n = 874). SDI: Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index.