Multiple linear regression analysis of prognostic factors for articular destruction.
| Dependent Variable | Independent Variable | Regression Coefficient | Standardized Regression Coefficient | p |
|---|---|---|---|---|
| Articular destruction A* | 0.711*** | < 0.0001 | ||
| Constant | −13.097 | 0.0455 | ||
| Initial total Sharp score | 0.590 | 0.332 | 0.0032 | |
| Swollen joint count after 12 wks | 1.365 | 0.278 | 0.0213 | |
| CRP after 12 wks | 1.761 | 0.228 | 0.0491 | |
| Patients’ pain after 12 wks† | 0.308 | 0.283 | 0.0229 | |
| Articular destruction B** | 0.728*** | < 0.0001 | ||
| Constant | −11.902 | 0.0383 | ||
| Initial total Sharp score | 0.477 | 0.272 | 0.0120 | |
| Mean swollen joint count†† | 3.521 | 0.407 | 0.0002 | |
| Mean CRP†† | 4.837 | 0.354 | 0.0021 |
↵* Determined by multiple linear regression analysis of relationship between initial total Sharp score and the ACR core set measure after 12 weeks’ treatment and the progression of articular destruction.
↵** Determined by multiple linear regression analysis with the initial total Sharp score and the mean values of measures over the 96 week study period as independent variables.
↵*** Multiple regression coefficient.
↵† Patients’ pain estimation after 12 weeks.
↵†† Mean of values determined every 12 weeks for 96 weeks.