Characteristics of initial responders, secondary responders, and nonresponders. Response according to the American College of Rheumatology Pediatric 30 response criteria (ACRpedi30).
| Feature | Initial Responders, N = 145 | Secondary Responders, N = 11 | Nonresponders, N = 23 |
|---|---|---|---|
| Total n = 179, F:M | 101:44 | 5:6 | 20:3 |
| Median age onset of JIA, yrs (IQR) | 6.3 (3.1–10.0) | 5.6 (3.4–10.0) | 4.7 (2.7–5.3) |
| Median duration from diagnosis to start of etanercept, yrs (IQR) | 3.5 (1.7–7.8) | 4.0 (3.3–6.6) | 3.1 (1.9–8.7) |
| JIA subtype (%) | |||
| Systemic JIA, n = 42 | 26 (62)* | 2 (5) | 14 (33) |
| Polyarticular RF−, n = 71 | 63 (89)** | 3 (4) | 5 (7) |
| Polyarticular RF+, n = 13 | 11 (85) | 0 (0) | 2 (15) |
| Oligoarticular extended, n = 37 | 31 (84) | 4 (11) | 2 (5) |
| Psoriatic arthritis, n = 10 | 9 (90) | 1 (10) | 0 (0) |
| Enthesitis related arthritis, n = 6 | 5 (83) | 1 (17) | 0 (0) |