Prevalence of SSc-associated autoimmune disease (AID) in French and Italian cohorts.
| Disease [n (%)] | SSc Patients from France, n = 585 | SSc Patients from Italy, n = 547 | p | Combined Population, n = 1132 |
|---|---|---|---|---|
| Sjögren’s syndrome | 44 (7.5) | 93 (17) | < 0.0001 | 137 (12) |
| Autoimmune thyroiditis | 23 (4) | 47 (8.5) | 0.025 | 70 (6) |
| Myositis | 19 (3) | 16 (3) | 0.86 | 35 (3) |
| Primary biliary cirrhosis | 14 (2) | 17 (3) | 0.37 | 31 (3) |
| Rheumatoid arthritis | 8 (1) | 3 (0.5) | 0.53 | 11 (1) |
| Systemic lupus erythematosus | 6 (1) | 3 (0.5) | 0.53 | 9 (1) |
| At least 1 AID associated with SSc | 87 (15) | 152 (28) | < 0.0001 | 239 (21) |
| At least 2 AID associated with SSc | 16 (3) | 14 (2.5) | 0.74 | 30 (3) |
| At least 3 AID associated with SSc | 2 (0.3) | 2 (0.3) | 0.59 | 4 (0.3) |