Table 3.

Mean ± standard deviation for SF-36 subscales and summary scales for the study population, cross-classified by presence of flares in the preceding year and severity or manifestations of flares.

No. of FlaresSeverityOrgan SystemManifestations
Without Flare, n = 242With Flares, n = 61One Flare, n = 50Two Flares, n = 11Mild/moderate, n = 18Severe, n = 32Single Organ, n = 53Multiorgan, n = 8Renal/NP, n = 26Musculoskeletal, n = 8Other, n = 19
Subscales
  Physical function73 ± 2666 ± 3065 ± 3059 ± 3164 ± 2566 ± 3268 ± 2852 ± 4068 ± 3348 ± 26*74 ± 14
  Role limitation due to physical problems55 ± 4431 ± 38††34 ± 3920 ± 3139 ± 4030 ± 4032 ± 3925 ± 3530 ± 3928 ± 3637 ± 40
  Bodily pain65 ± 2558 ± 2859 ± 2753 ± 3550 ± 2865 ± 2556 ± 2870 ± 2960 ± 2730 ± 16*63 ± 28
  General health41 ± 2235 ± 20†35 ± 2132 ± 2034 ± 1836 ± 2235 ± 2132 ± 1834 ± 2327 ± 1341 ± 19
  Vitality50 ± 2047 ± 2349 ± 2238 ± 2345 ± 2252 ± 2247 ± 2349 ± 1946 ± 2639 ± 2152 ± 19
  Social function73 ± 2464 ± 26†65 ± 2659 ± 2661 ± 2868 ± 2665 ± 2658 ± 3065 ± 2644 ± 24*74 ± 22
  Role limitation due to emotional problems59 ± 4445 ± 45†46 ± 4639 ± 4243 ± 4748 ± 4643 ± 4554 ± 4738 ± 4625 ± 3958 ± 46
  Mental health64 ± 1962 ± 2063 ± 1955 ± 2060 ± 2165 ± 1962 ± 2163 ± 1460 ± 2253 ± 1868 ± 19
Summary scales
  Physical health summary45 ± 941 ± 9†41 ± 940 ± 1140 ± 941 ± 941 ± 938 ± 842 ± 1034 ± 7*43 ± 8
  Mental health summary44 + 1142 ± 1243 ± 1238 ± 1341 ± 1244 ± 1342 ± 1244 ± 1343 ± 1236 ± 946 ± 11
  • p < 0.05;

  • †† p < 0.005, significant differences between patients with and without flares.

  • * p < 0.05, significant difference between patients with musculoskeletal flares and other flares. NP: neuropsychiatric.