Correlations of changes in plasma chemokines and clinical outcome measures after 12 weeks of treatment in patients with RA.
| Measure | CXCL10 | CXCL9 | CCL2 | CCL5 | CXCL8 |
|---|---|---|---|---|---|
| CRP | 0.005 (0.982) | 0.033 (0.883) | 0.007 (0.974) | 0.238 (0.287) | 0.284 (0.201) |
| ESR | 0.168 (0.454) | 0.019 (0.932) | 0.160 (0.476) | 0.416 (0.54) | 0.282 (0.203) |
| DAS28 ESR | 0.277 (0.212) | 0.094 (0.676) | 0.298 (0.179) | 0.174 (0.431) | 0.400 (0.065) |
| HAQ score | 0.154 (0.494) | 0.533 (0.011)* | 0.296 (0.182) | 0.271 (0.222) | 0.289 (0.192) |
| Physician global assessment | 0.119 (0.598) | 0.091 (0.687) | –0.034 (0.882) | 0.148 (0.511) | 0.172 (0.444) |
| Patient global assessment | –0.043 (0.849) | –0.226 (0.312) | 0.142 (0.528) | 0.263 (0.236) | 0.428 (0.047)* |
| Swollen joint score | 0.189 (0.399) | 0.074 (0.743) | 0.054 (0.813) | 0.162 (0.472) | 0.139 (0.537) |
| Tender joint score | 0.367 (0.093) | 0.122 (0.590) | 0.275 (0.216) | 0.218 (0.330) | 0.517 (0.014)* |
Results are expressed as correlation coefficient r (p value).
↵* p value < 0.05 is considered significant using Spearman’s rank correlation test. CRP: C-reactive protein; ESR: erythrocyte sedimentation rate; HAQ: Health Assessment Questionnaire.