Frequency and extent of thin-section computed tomographic findings (CT) in primary (1-SS) and secondary Sjögren’s syndrome (2-SS). Data on extent of thin-section CT findings are mean ± SD of the percentage of CT scores. P values were calculated by comparing data of 1-SS versus 2-SS using Fisher’s exact probability test for frequency and Mann-Whitney U test for extent of CT findings.
| All SS, n = 80 | 1-SS, n = 56 | 2-SS, n = 24 | p | ||||||
|---|---|---|---|---|---|---|---|---|---|
| CT Finding | N | (%) | Extent | N (%) | Extent | N (%) | Extent | N | Extent |
| Airspace consolidation | 13 | (16) | 1.6 ± 4.3 | 8 (14) | 2.4 ± 5.9 | 5 (21) | 3.5 ± 6.9 | 0.516 | 0.395 |
| Bronchiectasis | 18 | (23) | 6 ± 15.7 | 12 (21) | 3.6 ± 6.9 | 6 (25) | 4.2 ± 7.4 | 0.774 | 0.620 |
| Cysts | 30 | (38) | 6.3 ± 12.5 | 22 (39) | 6.5 ± 8.2 | 8 (33) | 5.6 ± 8 | 0.802 | 0.439 |
| Emphysema | 5 | (6) | 2.2 ± 12.5 | 2 (4) | 0.6 ± 3.1 | 3 (13) | 2.1 + 5.6 | 0.156 | 0.137 |
| Ground-glass opacities | 32 | (40) | 9.1 ± 20.3 | 20 (36) | 6 ± 8.1 | 12 (50) | 8.3 ± 8.5 | 0.320 | 0.103 |
| Honeycombing | 11 | (14) | 4.9 ± 14.7 | 4 (7) | 1.2 ± 4.3 | 7 (29) | 4.9 ± 7.7 | 0.014 | 0.010 |
| Ill-defined centrilobular nodule | 31 | (39) | 6.8 ± 11.4 | 20 (36) | 6 ±8.1 | 11 (46) | 7.6 ± 8.5 | 0.457 | 0.392 |
| Interlobular septal thickening | 57 | (71) | 18.3 ± 20.4 | 38 (68) | 11.3 ± 7.9 | 19 (79) | 13.2 ± 6.9 | 0.421 | 0.112 |
| Intralobular reticular opacities | 30 | (38) | 7.7 ± 16.3 | 20 (36) | 6 ± 8.1 | 10 (42) | 6.9 ± 8.4 | 0.624 | 0.549 |
| Mosaic perfusion | 19 | (24) | 12.3 ± 27.0 | 12 (21) | 3.6 ± 6.9 | 7 (29) | 4.9 ± 7.7 | 0.568 | 0.522 |
| Nonseptal linear or plate-like opacities | 13 | (16) | 1.6 ± 4.2 | 10 (18) | 3 ± 6.4 | 3 (13) | 2.1 ± 5.6 | 0.745 | 0.447 |
| Pleural thickening | 33 | (41) | 7.7 ± 15.0 | 20 (36) | 6 ± 8.1 | 13 (54) | 9 ± 8.5 | 0.143 | 0.150 |
| Thickening of BVB | 23 | (29) | 8.0 ± 18.0 | 16 (29) | 4.8 ± 7.6 | 7 (29) | 4.9 ± 7.7 | 1.000 | 0.969 |
| Traction bronchiectasis | 14 | (18) | 4.4 ± 13.3 | 7 (13) | 2.1 ± 5.6 | 7 (29) | 4.9 ± 7.7 | 0.107 | 0.096 |
Data in bold type indicate significant differences between 1-SS and 2-SS. BVB: bronchovascular bundles; n: number of patients with each thin-section finding.