HAQ, KPS, MHISS, MACTAR, and CHFS scores, as well as aesthetic burden, anxiety, and depression assessment at baseline visit, at followup visit and their differences, and responsiveness of the disability and handicap measures for the 49 patients with SSc.
| Baseline Evaluation | Followup Evaluation | Difference | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Outcome Measures (range) | Mean | SD | Minimum | Maximum | Mean | SD | Minimum | Maximum | Mean | SD | Minimum | Maximum | ES | SRM | p* |
| HAQ (0–3) | 1.2 | 0.6 | 0 | 2.4 | 1.4 | 0.9 | 0 | 3 | −0.2 | 0.6 | −1.4 | 0.8 | −0.38 | −0.41 | 0.01** |
| KPS (0–100) | 77.6 | 9 | 60 | 90 | 78 | 7.6 | 60 | 90 | −0.7 | 8.3 | −20 | 20 | −0.04 | −0.04 | 0.6 |
| MHISS (0–48) | 19.2 | 10.6 | 0 | 38 | 19.3 | 9.8 | 2 | 37 | −2.3 | 8.2 | −34 | 11 | −0.01 | −0.02 | 0.13 |
| MACTAR (0–30) | 14.7 | 5.8 | 4 | 25 | 16.8 | 5.5 | 5 | 26 | −2.3 | 6.3 | −14 | 14 | −0.37 | −0.34 | 0.01** |
| CHFS (0–90) | 20.1 | 16.5 | 0 | 55 | 22.7 | 16.6 | 0 | 62 | −2.6 | 9.3 | −26 | 17 | −0.16 | −0.28 | 0.055 |
| HADa (0–21) | 10.4 | 4.5 | 1 | 19 | 9.5 | 4.3 | 1 | 19 | 1 | 3.3 | −5 | −6 | 0.20 | 0.27 | 0.04** |
| HADd (0–21) | 7 | 3.9 | 0 | 15 | 6.6 | 3.6 | 1 | 16 | 0.4 | 2.8 | −6 | 6 | 0.11 | 0.15 | 0.30 |
| Aesthetic burden (0–10) | 5.5 | 2.3 | 1 | 9 | 4.5 | 2.7 | 0 | 9 | 0.5 | 1.8 | −2 | 5 | 0.46 | 0.60 | 0.28 |
↵*Comparisons were performed using paired samples t test.
↵**Difference is significant. SSc: systemic sclerosis; HAQ: Health Assessment Questionnaire; KPS: Karnofsky Performance Status Scale; MHISS: Mouth Handicap In Systemic Sclerosis Scale; MACTAR: McMaster-Toronto Arthritis Patient Preference Disability Questionnaire; CHFS: Cochin Hand Function Scale; HADa: Hospital Anxiety and Depression scale for Anxiety; HADd: Hospital Anxiety and Depression scale for Depression; ES: effect size; SRM: standardized response means. P value: comparison between outcome measures at baseline and at followup.