High-risk | Preexisting infections† | Incident Infections† | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
HPV Types | Events | Persistent Infection | No. of Cleared Infections | Events | Only at Next-to-last/Last Visit | Transient Infection | Persistent Infection | Duration of Persistence, mo, mean (95% CI) | No. of Cleared Infections | Cumulative No. of Events |
6 | 0 | 0 | 0 | 1 | 0/0 | 1 | 0 | — | — | 1 |
11 | 0 | 0 | 0 | 1 | 1/0 | 0 | 0 | — | — | 1 |
40 | 0 | 0 | 0 | 1 | 1/0 | 0 | 0 | — | 1 | |
42 | 1 | 0 | 1 | 1 | 0/0 | 0 | 1 | 19.0 | 0 | 2 |
54 | 0 | 0 | 0 | 3 | 1/1 | 0 | 1 | 12.8 | 0 | 3 |
55 | 1 | 0 | 1 | 2 | 0/0 | 0 | 2 | 6.1 (6.1–18.4) | 0/1** | 3 |
61 | 1 | 1 | 1 | 1 | 0/0 | 0 | 1 | 17.5 | 0 | 2 |
62 | 0 | 0 | 5 | 1/0 | 2 | 2 | 18.4 (18.4–19.8) | 0 | 5 | |
70 | 1 | 1 | 0/1** | 1 | 0/1 | 0 | 0 | — | — | 2 |
72 | 1 | 0 | 1 | 1 | 0/0 | 0 | 1 | 12.8 | 0 | 2 |
81 | 1 | 0 | 1 | 2 | 0/1 | 0 | 1 | 14.0 | 0/1** | 3 |
84 | 1 | 1 | 1 | 2 | 1/0 | 0 | 1 | 13.1 | 1 | 3 |
CP6108 | 1 | 0 | 1 | 1 | 0/0 | 0 | 1 | 6.5 | 0 | 2 |
Total no. | 8 | 3 | 7/1** | 22 | 5/3 | 3 | 11 | 1/2** | 30 | |
Overall no. | 36 (4) | 10 (1) | 32 (3)/2** | 68 | 16/10 | 9 | 33 | 1/5** | 104 |
† One patient can contribute toward more than 1 type of HIV infection.
* Each patient can contribute toward more than 1 episode of infection of the same type of HPV if there is reinfection after clearance. The overall numbers represent the sum of the low and high-risk HPV presented in this Table and Table 2A.
↵** Number of episode(s) of persistent HPV infection until next-to-last visit. Number in parentheses indicates the number of baseline infections with LEEP or cervical biopsy done. The number of persistent and cleared infections does not necessarily equal the total number of events of preexisting infections since a persistent infection could also be cleared. The total number of events for the incident infections equals the sum of the number of infections at the next-to-last or last visit, transient, and persistent infection. For the incident infections, only 1 out of 33 was cleared. HPV: human papilloma virus; LEEP: loop electrosurgical excision procedure.