Comparison of myocardial structure and function in patients with SLE and the control group with 2-dimensional echocardiography.
| SLE, n = 67 | Control, n = 40 | p | |
|---|---|---|---|
| LA, mm | 34.1 ± 4.8 | 31.4 ± 4.0 | < 0.05 |
| ESD, mm | 29.5 ± 3.8 | 27.0 ± 2.8 | < 0.05 |
| EDD, mm | 46.4 ± 3.3 | 45.5 ± 2.8 | NS |
| SWT, mm | 10.0 ± 1.1 | 9.2 ± 0.9 | < 0.05 |
| PWT, mm | 9.8 + 1.0 | 9.0 ± 2.8 | NS |
| EF, % | 59.0 ± 3.1 | 60.6 ± 2.7 | NS |
| ESV, ml | 50.9 ± 9.6 | 43.6 ± 7.7 | < 0.05 |
| EDV, ml | 124.6 ± 24.6 | 110.5 ± 16.7 | < 0.05 |
| SV, ml | 73.7 ± 16.4 | 66.9 ± 10.0 | NS |
| FS, % | 0.36 ± 0.1 | 0.4 ± 0.1 | NS |
| Cardiac output, l/min | 5.4 ± 1.4 | 4.8 ± 0.8 | NS |
| Cardiac index, l/min*m2 | 3.1 ± 0.8 | 2.8 ± 0.5 | NS |
| PW-E, cm/s | 76.8 ± 19.7 | 71.9 ± 13.2 | NS |
| PW-A, cm/s | 60.4 ± 22.1 | 54.7 ± 14.0 | NS |
| DT-E, ms | 201.2 ± 42.2 | 201.4 ± 24.1 | NS |
| PW-TDI-s, cm/s | 8.6 ± 1.7 | 12.6 ± 1.4 | < 0.05 |
| PW-TDI-e, cm/s | 11.7 ± 3.4 | 15.8 + 2.9 | < 0.05 |
| PW-TDI-a, cm/s | 8.7 ± 2.6 | 9.4 ± 2.5 | NS |
| E/e | 7.1 ± 3.6 | 4.7 ± 1.1 | < 0.05 |
| sPA, mm Hg | 25.8 ± 4.5 | 23.6 ± 3.2 | < 0.05 |
| MAPSE, cm | 1.5 ± 0.3 | 1.8 ± 0.2 | < 0.05 |
| TAPSE, cm | 2.0 ± 0.5 | 2.3 ± 0.3 | < 0.05 |
| LV mass (LVM), g | 160.7 ± 35.7 | 137.9 + 22.6 | < 0.05 |
| LV mass index, LVM/BSA | 92.6 ± 18.7 | 81.3 ± 10.9 | < 0.05 |
| LV mass index, LVM/m2.7 | 41.7 ± 9.7 | 35.1 ± 5.2 | < 0.05 |
| RWT | 0.423 ± 0.04 | 0.396 ± 0.05 | < 0.05 |
DT-E: deceleration time of mitral inflow; EF: left ventricular ejection fraction; EDD: left ventricular end-diastolic dimension; ESD: left ventricular end-systolic dimension; EDV: left ventricular end-diastolic volume; ESV: left ventricular end-systolic volume; FS: fractional shortening; LA: diameter of left atrium; LV: left ventricular; MAPSE: mitral annular plane systolic excursion; PW-A: peak velocity of late diastolic mitral inflow; PW-E: peak velocity of early diastolic mitral inflow; PCWP: estimated pulmonary capillary wedge pressure; PW-TDI-s: peak systolic myocardial velocity derived by pulsed wave Doppler tissue; PW-TDI-e: peak early diastolic myocardial velocity; PW-TDI-a: peak late diastolic myocardial velocity; RWT: relative wall thickness; SWT: septal wall thickness; PWT: posterior wall thickness; sPA: pulmonary artery systolic pressure; SLE: systemic lupus erythematosus; SV: stroke volume; TAPSE: tricuspid annular plane systolic excursion; NS: not significant.