Laboratory measures of SLE (early vs late onset).
| Early Onset | Late Onset | p | |
|---|---|---|---|
| ANA-positive | 1282 (97.0) | 149 (96.8) | 0.5 |
| Anti-dsDNA-positive | 514 (80.3) | 64 (79.0) | 0.4 |
| Anti-Sm-positive | 183 (29.9) | 8 (10.5) | < 0.0001* |
| Anti-Ro/SSA antibodies | 330 (33.5) | 32 (27.8) | 0.2 |
| Anti-RNP antibodies | 274 (28.8) | 16 (13.8) | < 0.0001* |
| Anti-La/SSB antibodies | 135 (14.4) | 12 (10.6) | 0.3 |
| Anti-Jo1 antibodies | 42 (4.5) | 1 (0.9) | 0.08 |
| Anti-Scl70 antibodies | 17 (1.9) | 4 (3.5) | 0.3 |
| Antiphospholipid-positive | 306 (50.0) | 32 (42.7) | 0.1 |
| Anticardiolipin-positive | 164 (58.0) | 16 (55.2) | 0.5 |
| Low serum levels of complements (ever) | 458 (41.8) | 31 (25.0) | < 0.0001* |
| pANCA | 29 (3.2) | 5 (4.4) | 0.4 |
| cANCA | 9 (1.0) | 3 (2.7) | 0.1 |
↵* Statistically significant. ANA: antinuclear antibody; dsDNA: double-stranded DNA; Sm: Smith; RNP: ribonucleoprotein; pANCA: perinuclear ANCA; cANCA: cytoplasmic ANCA.