Clinical manifestations of SLE (early vs late onset) at first database visit.
| Feature | Early Onset, n (%) | Late Onset, n (%) | p |
|---|---|---|---|
| Fever | 183 (16.7) | 10 (7.9) | 0.009* |
| Nephrotic syndrome | 64 (6) | 0 | 0.001* |
| Alopecia | 0 | 2 (2.5) | 0.016* |
| Arthralgias | 582 (52.7) | 75 (58.1) | 0.3 |
| Weight loss | 188 (17.3) | 25 (19.5) | 0.5 |
| Fatigue | 559 (50.9) | 70 (54.7) | 0.5 |
| Inflammatory arthritis | 238 (21.7) | 37 (29.1) | 0.07 |
| Deforming arthritis | 80 (7.3) | 12 (9.7) | 0.4 |
| Sicca complex | 77 (13.3) | 14 (16.5) | 0.4 |
| Fibromyalgia | 155 (23.6) | 18 (19.1) | 0.4 |
| Raynaud’s | 434 (39.3) | 61 (46.9) | 0.1 |
| Myositis | 28 (2.6) | 5 (4.0) | 0.4 |
↵* Statistically significant.