Table 1.

Diseases accompanied by salivary gland enlargement.

  1. Infection

    • Bacterial

      • Acute purulent

      • Chronic recurrent

    • Specific bacterial

      • Tuberculosis

    • Viral

      • Epidemic parotitis (rubulavirus)

      • Cytomegaly (cytomegalovirus)

      • Other (Kaposi sarcoma herpesvirus, Epstein-Barr virus, etc.)

  2. Obstructive electrolyte sialadenitis (+/− sialolithiasis)

  3. Sialadenosis

    • Endocrine disturbance (e.g., diabetes mellitus)

    • Psychogenic disturbance (e.g., bulimia)

    • Dystrophic disturbance (e.g., cachexia)

  4. Autoimmune disease

    • Sjögren’s syndrome

    • Autoimmune pancreatitis

  5. IgG4 sclerosing disease

  6. Granulomatous disease

    • Sarcoidosis

    • Wegener’s granulomatosis

  7. Neoplastic disease

    • Benign

    • Malignancies

  8. Iatrogenic

    • Radiation

    • Radio-iodine