Table 3.

Laser Doppler perfusion imaging findings in 3 groups of the study population. Mean (± SD) values of minimum, mean, and maximum perfusion are expressed as perfusion units.

TimepointGroupMinimum PerfusionMean PerfusionMaximum PerfusionSD Mean Value
BaselineSSc patients with PAH0.164 ± 0.0700.795 ± 0.1192.363 ± 0.4290.292 ± 0.050
SSc patients without PAH0.169 ± 0.0760.784 ± 0.1442.296 ± 0.5230.282 ± 0.048
Healthy controls0.198 ± 0.0670.852 ± 0.1872.786 ± 0.7730.305 ± 0.047
4 weeksSSc patients with PAH0.170 ± 0.0660.800 ± 0.1222.302 ± 0.4340.291 ± 0.047
SSc patients without PAH0.166 ± 0.0720.781 ± 0.1482.289 ± 0.5180.278 ± 0.043
Healthy controls0.190 ± 0.0640.848 ± 0.1922.744 ± 0.76230.311 ± 0.044
8 weeksSSc patients with PAH0.207 ± 0.084*0.911 ± 0.166**2.912 ± 0.0512*0.313 ± 0.051***
SSc patients without PAH0.166 ± 0.0700.774 ± 0.1842.294 ± 0.5330.284 ± 0.046
Healthy controls0.194 ± 0.0630.858 ± 0.1772.812 ± 0.7860.307 ± 0.048
16 weeksSSc patients with PAH0.210 ± 0.078*0.915 ± 0.178**2.911 ± 0.522*0.333 ± 0.049***
SSc patients without PAH0.170 ± 0.0760.790 ± 0.1442.290 ± 0.4930.284 ± 0.052
Healthy controls0.196 ± 0.0590.860 ± 0.1672.810 ± 0.7460.310 ± 0.050
  • PAH: pulmonary arterial hypertension.

  • * p < 0.05,

  • ** p < 0.001,

  • *** p < 0.01 compared with baseline.