Table 1.

Baseline characteristics of study subjects. Fatigue was measured using the Medical Outcomes Study Short Form-36 questionnaire vitality subscale. Scores are normalized with a mean of 50 and standard deviation of 10. Scores below 50 represent worse fatigue and above 50, more vitality. Values are mean (SD) unless otherwise indicated.

Canadian Subjects, n = 742US Subjects, n = 61
Age, yrs55.48 (12.39)51.44 (11.37)
Disease duration, yrs10.70 (8.98)7.48 (8.35)
Skin score (0–51)10.69 (9.62)8.20 (7.27)
Raynaud’s (0–10)2.83 (2.87)4.11 (3.00)
Shortness of breath (0–10)2.04 (2.60)2.32 (2.77)
Gastrointestinal symptoms (0–10)1.80 (2.60)1.87 (2.52)
Pain (0–10)3.65 (2.74)4.23 (2.48)
Number of fingertip ulcers1.28 (2.46)0.55 (1.47)
Swollen joint count (0–28)0.65 (2.32)0.30 (1.34)
Tender joint count (0–28)1.45 (3.78)0.98 (2.74)
Fatigue48.85 (21.70)42.34 (22.83)
Creatinine, umol/l83.77 (53.74)79.42 (35.45)
Patient assessment of severity (0–10)3.63 (2.54)4.25 (2.59)
Physician assessment of severity (0–10)2.85 (2.27)2.04 (1.78)
Females, no. (%)642 (86.50)55 (85.94)
Diffuse disease, no. (%)299 (40.30)31 (48.44)
White, no. (%)601 (81.00)58 (90.62)
Education > high school, no. (%)355 (47.84)48 (75.00)