Table 3.

Prevalence and levels in serum and cerebrospinal fluid (CSF) from cNPSLE patients, as determined at baseline and 6 months. Values are expressed sa median (min-max).

cNPSLE, Baseline, n = 23cNPSLE, 6 mo, n = 23p
Serum
  S100B levels*24.6 (19.8–164.3)24.6 (12.6–55.3)0.19
  S100B-positive (%)4 (17)1 (4)0.35
  S100B levels**65.7 (48–164.3)29.7 (22.8–55.3)0.07
CSF
  SB100 levels*265.4 (68.9–2500)154.2 (65.5–525.8)0.004
  S100B-positive (%)7 (30)00.009
  S100B levels**2325.7 (535.4–2500)130.2 (65.5–256.9)0.02
  • * All patients studied.

  • ** Positive patients with levels ≥ 3 SD above the mean levels in nonautoimmune patients.