Table 3.

The genotype frequencies of −373 A_nT_n polymorphism in the promoter region of IL-6 gene. Genotype identified by direct sequencing. Logistic regression analysis was applied to control for age and sex as covariables.

Loci (−373 A_nT_n)	Genotype	Patients with SLE, n = 151 (%)	Controls, n = 151 (%)	SLE vs Controls
Loci (−373 A_nT_n)	Genotype	Patients with SLE, n = 151 (%)	Controls, n = 151 (%)	p	OR (95% CI)
−373 A₉T₁₁	A₉T₁₁	21 (13.9)	28 (18.5)	0.116	0.577 (0.290 ∼ 1.145)
−373 A₉T₁₁	Other	130 (86.1)	123 (81.5)
−373 A₁₀T₁₀	A₁₀T₁₀	82 (54.3)	104 (68.9)	0.038	0.579 (0.345 ∼ 0.970)
−373 A₁₀T₁₀	Other	69 (45.7)	47 (31.1)
−373 A₁₀T₁₁	A₁₀T₁₁	48 (31.8)	19 (12.6)	<0.001	3.535 (1.839 ∼ 6.794)
−373 A₁₀T₁₁	Other	103 (68.2)	132 (87.4)

IL-6: interleukin 6; SLE: systemic lupus erythematosus.