Table 2.

Plasma cortisol levels (μg/dl) after stimulation with corticorelin; highest changes of the 2 postinjection values per test by treatment and time.

TreatmentsNo. TestsMean ± SD, μg/dlMedian, μg/dlMinimum/Maximum μg/dl
Test 1
  IR prednisone
  Screening phase215.5 ± 4.375.00−0.98/15.00
Test 2
  MR prednisone83.3 ± 5.762.50−3.98/13.85
  End of double-blind phase15
Test 2
  IR prednisone114.5 ± 3.913.01−1.02/12.00
  End of double-blind phase15
Test 3
  MR prednisone225.3 ± 4.075.00−2.00/13.01
  At end of study
  • IR: immediate release; MR: modified release.