Average disease activity and damage and number of events during the study.
| Measure score | No. Visits with Event | No. Patients with Score = 0 | Mean (SD) | Median (IQR) | No. Visits with Score = 0 | No. Visits with Score > 0 |
|---|---|---|---|---|---|---|
| Disease activity | ||||||
| BILAG Summary Score* | 13 | 5.3 (5.4) | 4 (6) | 79 | 469 | |
| BILAG General domain | 61 | 0.6 (1.4) | 0 (1) | 171 | 377 | |
| BILAG Mucocutaneous domain | 68 | 0.8 (1.7) | 0 (1) | 418 | 130 | |
| BILAG Neurological domain | 81 | 0.4 (1.4) | 0 (0) | 460 | 88 | |
| BILAG Musculoskeletal domain | 67 | 0.5 (1.2) | 0 (1) | 200 | 348 | |
| BILAG Cardiovascular & Respiratory domain | 85 | 0.3 (1.0) | 0 (0) | 501 | 47 | |
| BILAG Vasculitis domain | 81 | 0.2 (0.6) | 0 (0) | 461 | 87 | |
| BILAG Hematology domain | 41 | 0.9 (1.4) | 1(1) | 247 | 301 | |
| BILAG Renal domain | 55 | 1.6 (2.6) | 0 (3) | 356 | 191 | |
| SLEDAI-2K Score | 12 | 5.2 (5.2) | 4 (4) | 91 | 458 | |
| Disease damage — SDI** | ||||||
| No or minimal damage (SDI ≤ 1) | 265 | 71 | 0.5 (1.0) | 0 (1) | 221 | 88 |
| More than minimal damage (SDI > 1) | 44 | |||||
| Disease course | ||||||
| Patient/parent-rated change in health | ||||||
| Improved | 176 | |||||
| Same | 213 | |||||
| Worse | 49 | |||||
| Physician assessment of overall disease | ||||||
| Improved | 62 | |||||
| Same | 305 | |||||
| Worse | 76 | |||||