Genotypic and allelic frequencies of TLR4 rs4986790 polymorphism in patients with biopsy-proven giant cell arteritis (GCA) and controls.
| TLR4 | GCA patients n (%) | Controls n (%) | p | OR (95% CI) |
|---|---|---|---|---|
| rs4986790 | n = 210 | n = 678 | ||
| Genotype | ||||
| A/A | 172 (81.9) | 601 (88.6) | 0.01 | 0.58 (0.37–0.91) |
| A/G | 38 (18.1) | 77 (11.4) | 0.01 | 1.72 (1.10–2.69) |
| G/G | 0 (0) | 0 (0) | — | — |
| Allele | ||||
| A | 382 (91.0) | 1279 (94.3) | 0.01 | 0.61 (0.40–0.93) |
| G | 38 (9.0) | 77 (5.7) | 0.01 | 1.65 (1.08–2.52) |
OR: odds ratio; CI: confidence interval.