Table 1.

Characteristics of patients with systemic sclerosis (SSc).

CharacteristicPatients, n = 87
Age, mean ± SD, yrs55.2 ± 13.2
Disease duration, yrs, mean ± SD7.2 ± 7.5
Disease duration < 5 yrs, n (%)31 (35.6)
Weight, kg, mean ± SD66.7 ± 11.6
Height, m, mean ± SD162.2 ± 8.8
FVC % predicted, mean ± SD97.3 ± 25
FVC < 75% predicted, n (%)26 (29.9)
DLCO/AV % predicted, mean ± SD77.5 ± 17.2
DLCO/AV < 75% predicted, n (%)36 (41.4)
Interstitial lung disease on HRCT, n (%)47 (54)
sPAP by echocardiography, mmHg, mean ± SD32.4 ± 10
sPAP > 40 mmHg, n (%)12 (13.8)
PAH by right-heart catheterization, n (%)7 (8)
Left ventricular ejection fraction %, mean ± SD67.9 ± 5.3
Diastolic left ventricular dysfunction, n (%)27 (33.3)
Left ventricular mass, g, mean ± SD160 ± 47
Active or healed digital ulcers, n (%)24 (27.6)
Acroosteolysis, n (%)18 (21.2)
Calcinosis, n (%)20 (23.5)
Knee pain, n (%)34 (39)
Hemoglobin, g/l, mean ± SD12.9 ± 1.3
Creatinine, μmol/l, mean ± SD72 ± 16.5
CRP, mg/l, mean ± SD7.4 ± 12.2
Creatine phosphokinase, IU/l, mean ± SD129 ± 290
Antinuclear antibodies > 1/160, n (%)65 (74.7)
Medsger severity scale, n = 1–2; n = 3–453; 34
European activity score (EAS), mean ± SD1.77 ± 1.64
EAS > 3, n (%)15 (17.2)
sHAQ, mean ± SD0.81 ± 0.62
sHAQ > 1, n (%)26 (37.7)
  • DLCO: diffusion capacity for carbon monoxide; HRCT: high-resolution computed tomography; FVC: forced vital capacity; sPAP: systolic pulmonary artery pressure; PAH: pulmonary arterial hypertension; CRP: C-reactive protein; sHAQ: systemic sclerosis Health Assessment Questionnaire. AV: alveolar volume.