Table 1.

Clinical, laboratory profile and sicca features of DEMS/SAPS patients.

PatientDryness of:Other Clinical FeaturesSchirmer TestRose-Bengal StainImmunological Profile
1Eyes and mouthArthralgiasAARF, anti-TPO
2EyesTelengiectasias, RPAAANA, anti-TPO
3Eyes and mouthMorning stiffness, arthralgiasAAANA, anti-TPO
4Eyes and mouthNoneNANANA, RF, anti-TPO, anti-Tg
5Eyes and mouthMigraines, arthralgias, fibromyalgia-like features, RPNAANA, anti-TPO, anti-Tg
6MouthArthralgiasNNAnti-TPO, anti-Tg
7Eyes and mouthDry coughNANAAnti-TPO, anti-Tg
8Eyes and mouthMorning stiffness, arthralgias, arthritis, RPNAAnti-TPO
9Eyes and mouthParotid gland enlargement, thrombocytopeniaNAANA, anti-TPO, anti-Tg
10Eyes and mouthMigrainesNNNeg
11MouthNoneNNNeg
12Eyes and mouthNoneNNNeg
13Eyes and mouthArthralgias, carpal tunnel syndromeNNNeg
14Eyes and mouthFibromyalgia-like featuresNANeg
15Eyes and mouthArthralgiasAAANA
16Eyes and mouthArthralgiasANANA, anti-TPO
17MouthNNAnti-TPO
18Eyes and mouthArthralgiasNNANA, anti-TPO
19Eyes and mouthArthritisANAANA, anti-TPO
20Eyes and mouthPhotosensitive rashANANA, anti-TPO
21Eyes and mouthArthralgias-Myalgias-RPNNNeg
22Eyes and mouthArthralgiasANANA
23Eyes and mouthNoneNNANeg
24Eyes and mouthNoneNNNeg
25EyesNoneNANAANA, anti-TPO, anti-Tg
26Eyes and mouthArthralgiasNNNeg
27EyesNoneAARF, anti-TPO
  • DEMS: dry eyes and mouth syndrome; SAPS: sicca asthenia polymyalgia syndrome; RF: rheumatoid factor; anti-TPO: antibodies to thyroid peroxidase; TG: thyroglobulin; ANA: antinuclear antibodies; NA: not applicable; RP: Raynaud’s phenomenon. N: normal, A: abnormal.