Table 1.

Epidemiological, clinical, and laboratory data of patients with systemic sclerosis (SSc).

Limited SScNo. of Patients Diffuse SScTotal
Male/female4/102/56/15
Age, mean yrs4547
Race (Caucasian/African Brazilian)11/35/216/5
Mean disease duration prior to the skin biopsy, yrs54—
Followup, mo148107127
Raynaud’s phenomenon14721
Vascular cutaneous ulcers6 (5)*3 (3)*9 (8)*
Telangiectasis7 (5)**4 (3)**10 (8)**
Calcinosis819
Esophageal disease13518
Polyarthralgia9 (5)†3 (3)†13 (8)†
Intestinal202
Pulmonary
  Interstitial lung disease10414
  Vascular disease123
Heart358
Scleroderma renal crisis011
Antinuclear antibody11617
Anticentromere antibody404
Anti-Scl-70336

  • ↵* HLA-G-negative patients with vascular cutaneous ulcers (p = 0.0004);

  • ↵** HLA-G-negative patients with telangiectasias (p = 0.008);

  • † HLA-G-negative patients with inflammatory polyarthralgia (p = 0.02).