Correlations between biomarkers at baseline (Week 0).
| Biomarker | IL-18 | MMP-9 | TIMP-1 | SAA | E-selectin |
|---|---|---|---|---|---|
| MMP-9 | NS | ||||
| TIMP-1 | r = 0.219, p = 0.0049 | r = 0.289, p = 0.0002 | |||
| SAA | NS | r = 0.201, p = 0.0100 | r = 0.198, p = 0.0110 | ||
| E-selectin | r = 0.177, p = 0.0237 | r = 0.269, p = 0.0005 | r = 0.248, p = 0.0014 | NS | |
| CRP | NS | r = 0.217, p = 0.0054 | r = 0.242, p = 0.0018 | r = 0.656, p < 0.0001 | NS |
CRP: C-reactive protein; IL-18: interleukin-18; MMP-9: matrix metalloproteinase 9; NS: not significant; SAA: serum amyloid A; TIMP-1: tissue inhibitor of matrix metalloproteinase 1.