Clinical characteristics of patients with APS and control groups.
| Characteristics | APS Patients | Control Groups | |||
|---|---|---|---|---|---|
| A1, n = 26 | A2, n = 10 | B, n = 36 | C, n = 36 | D, n = 36 | |
| Age, yrs, mean (range) | 38 (28–48) | 39 (30–48) | 37 (30–43) | 37 (22–48) | 36 (27–50) |
| Abortions, mean (range) | 2.88 (1–8) | 2.60 (1–9) | 2.89 (2–7) | — | — |
| Abortions, < 10 wks, mean (range) | 1.64 (0–8) | 1.10 (0–5) | 1.89 (0–4) | — | — |
| Abortions, > 10 wks, mean (range) | 1.16 (0–7) | 1.50 (0–4) | 0.92 (0–3) | — | — |
| Live-born babies, mean (range) | 0.23 (0–2)* | 0.40 (0–4)* | 0.44 (0–3) | 1.64 (1–3) | — |
| Complications, n (%) | |||||
| Ischemic stroke | 0 (0) | 6 (60) | — | — | — |
| Deep venous thrombosis | 0 (0) | 3 (30) | — | — | — |
| Retinal thrombosis | 0 (0) | 1 (10) | — | — | — |
| Pulmonary embolism | 0 (0) | 1 (10) | — | — | — |
| Epilepsy | 1 (3.8) | 3 (30)** | — | — | — |
| Migraine | 1 (3.8) | 2 (20) | — | — | — |
| Livedo reticularis | 1 (3.8) | 3 (30)** | — | — | — |
| Abruptio placentae | 1 (3.8) | 0 (0) | — | — | — |
| Preeclampsia | 1 (3.8) | 1 (10) | — | — | — |
A1: obstetric APS without thrombosis; A2: obstetric APS with thrombosis; B: women with spontaneous recurrent abortions without antiphospholipid antibodies; C: healthy parous controls; D: health nonparous controls.
↵* Analysis of variance post hoc test, p < 0.001 vs parous C.
↵** Pearson chi-square, p < 0.05 vs A1.