Statistical analysis of age at RA onset using parametric test.
| Age at Disease Onset | Bivariate | Multivariate | |||
|---|---|---|---|---|---|
| N (%) | Mean yrs (SD) | p, β (95% CI) | p, β (95% CI) | ||
| SE | + | 240 (59) | 50 (± 17) | 0.12, −2.46 (−5.58; 0.65) | 0.16, −2.07 (−4.95; 0.81)*† |
| − | 171 (41) | 52 (± 14) | |||
| CCP | + | 222 (54) | 50 (± 15) | 0.07, −2.82 (−5.90; 0.26) | 0.52, −0.93 (−3.81; 1.94)*† |
| − | 189 (46) | 53 (± 16) | |||
| SE/CCP | 151 (37) | 48 (± 14) | |||
| double-positive | 0.05, −4.01 (−8.12−0.10) | 0.15, −2.7 (−6.35−0.95)*† | |||
| SE/CCP | 100 (24) | 53 (± 18) | |||
| double-negative | |||||
| Duration of disease | <10−3, −0.76 (−0.92; −0.61) | <10−3, −0.75 (−0.90; −0.59)* | |||
↵* Adjusted by sex. †Adjusted by duration of disease. SE: shared epitope; CCP: citric citrullinated peptide.