Clinical and radiographic outcome in patients with juvenile PsA and other subtypes of JIA. Values are number (%) of patients or mean ± standard deviation.
| PsA, n = 31 | Oligoarthritis, n = 137 | p vs PsA | Polyarthritis, n = 68 | p vs PsA | ERA, n = 55 | p vs PsA | |
|---|---|---|---|---|---|---|---|
| Variables assessed within first 15 yrs after onset | |||||||
| Psoriasis confirmed by a dermatologist | 12 (39) | 0 | < 0.001 | 0 | < 0.001 | 1 (2) | < 0.001 |
| Nail pitting | 7 (23) | 4 (3) | < 0.001 | 2 (3) | < 0.001 | 4 (7) | 0.041 |
| Dactylitis | 13 (42) | 9 | < 0.001 | 2 (3) | < 0.001 | 3 (6) | < 0.001 |
| Enthesitis | 1 (3) | 1 (0) | NS | 1 (0) | NS | 24 (44) | 0.001 |
| Positive ANA | 10 (32) | 51 (37) | NS | 19 (28) | NS | 7 (13) | 0.029 |
| Uveitis | 6 (19) | 27 (20) | NS | 11 (16) | NS | 11 (20) | NS |
| Variables assessed median 15 yrs after onset | |||||||
| Total cumulative no. of affected joints | 12.7 ± 13.2 | 5.2 ± 6.1 | 0.004 | 22.5 ± 13.2 | 0.001 | 11.6 ± 12.6 | NS |
| No. of mobility-restricted joints, range 0–68 | 3.4 ± 8.2 | 2.3 ± 5.2 | NS | 9.7 ± 11.6 | 0.009 | 4.6 ± 9.0 | NS |
| Remission without medication at least 1 yr | 17 (55) | 74 (54) | NS | 29 (43) | NS | 24 (44) | NS |
| Inactive disease* | 20 (65) | 93 (70) | NS | 32 (47) | NS | 27 (49) | NS |
| Hips, radiographic grade ≥ 2 | 6 (19) | 16 (12) | NS | 21 (31) | NS | 14 (26) | NS |
| Ankles, radiographic grade ≥ 2 | 5 (16) | 23 (17) | NS | 25 (37) | 0.038 | 12 (22) | NS |
| Peripheral joints, grade 3–5 | 7 (23) | 18 (13) | NS | 31 (46) | 0.029 | 14 (26) | NS |
| Radiographic sacroiliitis | 0 | 0 | NS | 0 | NS | 19 (36) | < 0.001 |
| Using antirheumatic drugs 23 yrs after onset** | |||||||
| Still on DMARD | 8 (29) | 9 (8) | 0.003 | 8 (18) | NS | 7 (13) | NS |
| On anti-TNF agents | 4 (14) | 4 (3) | 0.050 | 4 (9) | NS | 3 (8) | NS |
| On DMARD and/or anti-TNF agents | 10 (33) | 9 (8) | < 0.001 | 10 (22) | NS | 9 (18) | NS |
| On NSAID | 8 (29) | 25 (23) | NS | 8 (18) | NS | 14 (35) | NS |
| On prednisolone | 4 (14) | 2 (2) | 0.016 | 3 (7) | NS | 1 (3) | NS |
↵* Remission with or without medication for at least 6 months,
↵** n = 28 for PsA, n = 40 for ERA, n = 110 for oligoarthritis, n = 45 for polyarthritis. PsA: psoriatic arthritis, ERA: enthesitis related arthritis, NS: not statistically significant, ANA: antinuclear antibodies, DMARD: disease modifying antirheumatic drugs, TNF: tumor necrosis factor, NSAID: nonsteroidal antiinflammatory drugs.