Table 3.

Early determinants for differentiation between juvenile PsA (n = 31) and all other JIA subtypes (n =305) as well as oligoarticular or polyarticular JIA (n = 205).

Variables Assessed at Disease OnsetUnivariate Analyses*Multivariate Analysis**
OR95% CIpOR95% CIp
PsA vs all other subtypes (n = 336)
  Female sex1.670.70–4.010.249
  Onset age ≥ 6 yrs1.970.85–4.550.112
  Psoriasis in first-degree relative26.3510.84–64.07< 0.00130.8610.68–89.14< 0.001
  Psoriasis in patient14.404.11–50.51< 0.00112.062.26–64.400.004
  Dactylitis9.903.93–24.95< 0.00110.972.96–40.62< 0.001
  Small-joint arthritis2.060.98–4.330.050
  Toe arthritis2.170.97–4.850.061
  Ankle arthritis1.990.94–4.220.071
  Toe and/or ankle involvement2.731.22–6.130.0153.041.07–8.640.038
  Finger arthritis2.030.95–4.330.067
PsA vs oligo–/polyarthritis (n = 236)***
  Female sex1.080.44–2.650.872
  Onset age ≥ 6 yrs2.631.13–6.160.0264.411.61–12.120.004
  Dactylitis3.403.19–22.10< 0.00114.934.79–47.54< 0.001
  Ankle arthritis1.920.89–4.120.096
  Toe arthritis2.090.91–4.800.082
  Toe and/or ankle involvement2.621.15–5.960.022
  Hip involvement3.391.09–10.540.035
  • * DRB1*01, DRB1*04, DPB1*02, DPB1*03, wrist or knee arthritis, nail pitting, ANA, persistently elevated ESR, and cumulative numbers of affected joints within the first 6 months of disease were not associated with diagnosis of PsA in univariate analyses (p ≥ 0.10, data not shown).

  • ** Results of multiple logistic regression analysis identifying determinants of diagnosis of PsA. Variables associated with PsA in univariate analyses (p < 0.10) were included.

  • *** Psoriasis in patient or relative is an exclusion criterion from oligoarthritis and polyarthritis and could not be analyzed as an independent variable in the analyses of factors that differentiated PsA from either oligoarthritis or polyarthritis.