Locus | AOSD, n (%) | Controls, n (%) | p | OR (95% CI) | |
---|---|---|---|---|---|
Allele | |||||
FcγRIIA | R131 | 64 (32.7) | 80 (26.5) | 0.138 | 1.34 (0.91–1.99) |
H131 | 132 (67.3) | 222 (73.5) | |||
FcγRIIIA | F176 | 137 (69.9) | 223 (73.9) | 0.336 | 0.823 (0.55–1.23) |
V176 | 59 (30.1) | 79 (26.1) | |||
FcγRIIIB | NA2 | 90 (45.9) | 135 (44.7) | 0.789 | 1.05 (0.73–1.51) |
NA1 | 106 (54.1) | 167 (55.3) | |||
Genotype | |||||
FcγRIIA | R/R131 | 8 (8.2) | 10 (6.6) | ||
R/H131 | 48 (49.0) | 60 (39.7) | 0.251 | ||
H/H131 | 42 (42.9) | 81 (53.6) | |||
R/R131 + R/H131 | 56 (57.1) | 70 (46.3) | 0.096 | 1.54 (0.92–2.57) | |
FcγRIIIA | F/F176 | 45 (45.9) | 79 (52.3) | ||
V/F176 | 47 (48.0) | 65 (43.0) | 0.589 | ||
V/V176 | 6 (6.1) | 7 (4.6) | |||
F/F176 + V/F176 | 92 (93.8) | 144 (95.3) | 0.606 | 0.75 (0.24–2.28) | |
FcγRIIIB | NA2/NA2 | 19 (19.4) | 30 (19.9) | ||
NA1/NA2 | 52 (53.1) | 75 (49.7) | 0.855 | ||
NA1/NA1 | 27 (27.6) | 46 (30.5) | |||
NA2/NA2 + NA1/NA2 | 71 (72.4) | 105 (69.5) | 0.621 | 1.15 (0.66–2.02) |