Table 2.

Mean 6-minute walk distance (6MWD), resting, minimum, and drop in oxygen saturation (SpO₂), percentage predicted forced vital capacity (FVC%), and percentage predicted carbon monoxide diffusing capacity (DLCO%) compared by ANOVA between idiopathic pulmonary fibrosis (IPF) and scleroderma (SSc)-interstitial lung disease (ILD) (Table 2A); and between SSc subgroups (Table 2B). All data reported as mean (95% CI).

Table 2A
	IPF, n = 46	ILD, n = 27	p
6MWD, m	379 (347–411)	349 (308–391)	0.27
Resting SpO₂, %	96 (95–96)	97 (97–98)	0.003
Minimum SpO₂, %	87 (86–89)	92 (90–94)	0.002
Drop in SpO₂	8 (6–9)	6 (4–8)	0.07
FVC%	75 (69–81)	64 (57–71)	0.02
DLCO%	46 (41–52)	44 (38–51)	0.68

Table 2B
	ILD, n = 27	PAH, n = 12	Neither, n = 13	Both, n = 17	p	Tukey Results
6MWD, m	349 (302–397)	315 (243–387)	313 (244–382)	312 (251–372)	0.7029	NA
Resting SpO₂, %	97 (97–98)	97 (97–99)	98 (97–99)	96 (95–97)^*	0.2191	NA
Minimum SpO₂, %	92 (89–94)	92 (88–95)	94 (90–97)	87 (84–90)	0.0129	Both different from ILD and Neither
Drop in SpO₂, %	6 (3–8)	5 (1–8)	4 (1–7)	9 (7–12)	0.0633	NA
FVC%	64 (58–69)	96 (87–106)^**	91 (83–99)	62 (55–69)	< 0.0001	ILD and Both different from PAH and Neither
DLCO%	44 (37–51)^***	58 (46–70)^†	62 (52–72)	37 (28–46)^††	0.0017	Both different from PAH, ILD, and Neither; ILD different from Neither

↵* n = 18;
↵** n = 10;
↵*** n = 26;
↵† n = 9;
↵†† n = 16. SSc-ILD: SSc with interstitial lung disease; SSc-PH: SSc with pulmonary hypertension; SSc-Both: SSc with both ILD and PH; SSc-Neither: SSc with neither ILD nor PH.