Multiple regression* analysis of APOH promoter variants for SLE disease status, nephritis, and subclinical cardiovascular disease [carotid plaque and intima-media thickness (IMT)].
| Values of p** | ||||
|---|---|---|---|---|
| SLE | Nephritis | Carotid Plaque | Carotid IMT | |
| rs8178819 (–1219G>A) | 0.016 | 0.014 | 0.344 | 0.887 |
| rs3760290 (–1190G>C) | 0.982 | 0.790 | 0.070 | 0.322 |
| rs8178820 (–759A>G) | 0.182 | 0.185 | 0.884 | 0.903 |
| rs3760292 (–643T>C) | 0.016 | 0.944 | 0.003 | 0.036 |
| (–38G>A) | 0.295 | 0.200 | 0.022 | 0.836 |
| rs8178822 (–32C>A) | 0.646 | 0.344 | 0.033 | 0.753 |
↵* SLE risk was analyzed under additive model while lupus nephritis and carotid plaque and IMT under dominant model.
↵** Adjusted for age for SLE and nephritis risk; adjusted for age, high-density lipoprotein-C, low-density lipoprotein-C, cholesterol, and triglycerides for carotid plaque and IMT. SLE: systemic lupus erythematosus.