Table 4.

Percentage of respondents with additional symptoms. The unexplained musculoskeletal pain group and arthralgia group were compared to the control cohort. The denominator in each cell indicates the number of survey respondents who provided a response for that symptom.

SymptomControls Reporting Symptom(s), n (%)Arthralgia Group Reporting Symptom(s), n (%)
Back pain43/936 (4.6)118/478 (24.7)*
Fatigue37/936 (4)138/478 (28.9)*
Chest pain18/936 (2)68/474 (14.3)*
Joint pain61/938 (6.5)385/474 (79.5)*
Muscle pain or weakness42/939 (4.5)185/479 (38.6)*
Shortness of breath47/936 (5)69/477 (14.5)*
No. of symptoms
No additional symptoms**780/936 (83.3)59/472 (12.5)
  1**104/936 (11.1)165/472 (35.0)
  2**33/936 (3.5)105/472 (22.2)
  3**9/936 (1.1)68/472 (14.4)
  4**5/936 (0.5)38/472 (8.1)
  5**4/936 (0.4)24/472 (5.1)
  6**1/936 (0.1)13/472 (2.8)
  • * Chi-square analysis indicated a statistically significant difference compared to the control group (p < 0.001).

  • ** Additional symptoms include back pain, joint pain, muscle pain and weakness, fatigue, chest pain, and/or shortness of breath.