Table 2.

Minimal important difference (MID) estimates for the HAQ-DI.

Patient-rated Overall StatusHAQ-DI Change, mean (SD)95% CIEffect Sizep
Much better (n = 11)−0.57 (0.67)−1.01 to −0.120.74< 0.0001
Somewhat better (n = 35)−0.09 (0.42)−0.23 to 0.050.120.08
Same (n = 120)0.03 (0.32)−0.030 to 0.090.04
Somewhat worse (n = 50)0.15 (0.33)0.060 to 0.250.200.02
Much worse (n = 9)0.50 (0.13)0.40 to 0.600.65< 0.0001
  • HAQ-DI scored from 0 (no disability) to 3 (severe). HAQ-DI change score = HAQ score at most recent visit – score at previous visit. Negative score indicates improvement.