Autoantibody profiles, histological scores, and ß1i staining using K463 of different patient groups. Staining of ß1i using K463 and Chisholm-Mason grade were negatively correlated (Spearman r = −0.4611, p = 0.0135). No correlation was found between Chisholm-Mason grade and ß2i or ß5i staining (data not shown). Anti-Ro and anti-La antibodies were determined using automated fluorescence immunoassays (EliA, UniCap 100, Phadia, Freiburg, Germany.
| Diagnosis | Sex | Mean Age, yrs | Ro, no. | La, no. | Chisholm-Mason Grade | ß1i Expression, no. | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| F, no. | M, no. | 1 | 2 | 3 | 4 | 0 | 1 | 2 | ||||
| pSS | 14 | 0 | 50.4 | 13 | 13 | 0 | 1 | 5 | 8 | 10 | 3 | 1 |
| sSS | 3 | 0 | 42.7 | 2 | 1 | 0 | 0 | 0 | 3 | 3 | 0 | 0 |
| Sicca Symptoms | 9 | 2 | 54.7 | 3 | 0 | 5 | 6 | 0 | 0 | 3 | 8 | 0 |
pSS: primary Sjögren’s syndrome; sSS: secondary SS.