Table 1.

Odds ratios (95% confidence intervals) from multivariate logistic and ordered logit analyses*.

SLEDAI-2KSLICC/ACR DI
AlopeciaRashTotal CutaneousAlopeciaScarringTotal Cutaneous
Current smoking1.08 (0.27, 4.38)6.18 (1.63, 23.40)1.83 (0.69, 4.89)1.95 (0.75, 5.06)4.70 (1.04, 21.18)2.73 (1.10, 6.81)
Age (yrs)0.10 (0.95, 1.05)1.01 (0.95, 1.07)0.99 (0.95, 1.03)1.00 (0.97, 1.04)1.01 (0.95, 1.07)1.00 (0.97, 1.04)
Female**0.90 (0.07, 11.69)1.09 (0.20, 5.77)2.78 (0.32, 24.24)**3.51 (0.41, 9.88)
Caucasian0.94 (0.23, 3.87)4.20 (0.39, 45.58)1.43 (0.44, 4.66)1.12 (0.38, 3.27)0.31 (0.05, 1.87)0.83 (0.30, 2.28)
Disease duration1.02 (0.96, 1.09)0.97 (0.90, 1.04)0.99 (0.95, 1.04)1.05 (1.00, 1.09)1.02 (0.95, 1.11)1.05 (1.00, 1.09)
Antimalarial use1.29 (0.32, 5.09)2.86 (0.47, 17.46)1.74 (0.58, 5.21)2.28 (0.79, 6.62)0.32 (0.07, 1.41)1.63 (0.63, 4.23)
ANA positivity1.53 (0.28, 8.23)0.49 (0.10, 2.34)0.79 (0.27, 2.27)0.79 (0.29, 2.16)0.61 (0.12, 3.13)0.74 (0.29, 1.92)
Anti-dsDNA positivity1.23 (0.35, 4.28)3.93 (0.89, 17.36)1.66 (0.63, 4.42)0.65 (0.23, 1.83)**0.54 (0.20, 1.48)
Anti-SSA antibody1.76 (0.51, 6.15)1.09 (0.26, 4.64)1.22 (0.46, 3.20)1.74 (0.70, 4.34)0.47 (0.09, 2.41)1.36 (0.57, 3.22)
  • * Logistic analyses when the outcome was a single item, and ordered logit analyses when the outcome was the total cutaneous score (or overall total score).

  • All clinical variables reflect current status at time of study visit.

  • ** Sex was perfectly correlated with alopecia on the SLEDAI-2K, and with SLICC/ACR-DI scarring; thus this variable had to be removed from the given model for proper estimation. Similarly, anti-dsDNA positivity was perfectly correlated with SLICC/ACR-DI scarring, and had to be removed from the model when examining this outcome. SLEDAI-2K: Systemic Lupus Erythematosus Disease Activity Index, version 2000. SLICC/ACR-DI: Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index.