Patients with juvenile idiopathic arthritis qualifying for liver biopsy per ACR guidelines.
| Comorbidities/Potential Risk Factors | No. of Patients | Liver Biopsy Done |
|---|---|---|
| Macrophage activation syndrome — chronic | 1 | No |
| Infliximab-induced autoimmune hepatitis | 1 | Yes |
| Severe obesity | 1 | Yes |
| Chronic or recurrent sinusitis or otitis media treated with antibiotics | 4* | No |
| Safety laboratory surveillance within 3 days of MTX intake | 2* | No |
| Congenital abnormality: tetralogy of Fallot, abdominal pain with collapsed gall bladder | 1 | No |
| Congenital abnormality: jejunal atresia with microcolon, short-gut syndrome with multiple antibiotics | 1 | No |
| Total patients | 11 |
↵* One patient fulfilled both features and was counted only in the methotrexate (MTX) laboratory category. For additional details see Tables 1 and 2.