Table 1.

Characteristics of the study populations.

Patients Treated with MTXPatients not Treated with MTX, Laboratory Testing Available, n = 286
Laboratory Testing Available, n = 198No Laboratory Testing Available, n = 104
Age, yrs, mean (SD)12.0 (4.9)11.9 (5.4)13.0 (4.7)
Disease duration, yrs, mean (SD)4.9 (4.0)4.8 (5.0)4.7 (2.9)
Race, no. (%)
  African American7 (4)3 (3)20 (7)
  Caucasian175 (89)98 (94)250 (87)
  Other6 (3)*6 (2)
  Unknown6 (3)3 (3)10 (3)
Gender, no. (%)
  Male42 (21)25 (24)98 (34)
  Female155 (79)79 (76)188 (66)
JRA onset type, no. (%)
  Pauciarticular57 (29)25 (24)183 (64)
  Polyarticular116 (59)67 (65)73 (26)
  Systemic24 (12)11 (11)29 (10)
JIA subtypes, no. (%)
  Enthesitis related1 (0.5)1 (1)4 (1)
  Extended oligoarticular20 (10)13 (13)14 (5)
  Persistent oligoarticular38 (19)11 (10)159 (56)
  Polyarticular RF−100 (51)58 (57)70 (25)
  Polyarticular RF+13 (7)9 (9)7 (2)
  Psoriatic1 (0.5)2 (1)
  Systemic24 (12)11 (10)29 (10)
  • None of the differences between methotrexate-treated patients that were included in the study and those who were excluded because of surveillance laboratory testing reached statistical significance.

  • * 2 multiracial African American/Caucasian, 1 American Indian, 1 Alaska native, 2 Asian.