Clinical features in patients with single myositis-specific autoantibody (MSA) or myositis-associated autoantibody (MAA). Four patients not included in the table had 2 autoantibodies: 2 with PM-Scl/Ku, 1 with PM-Scl/MJ, 1 with MJ/Mi-2. Four patients also possessed the anti-Sm autoantibody, which is not an MSA or MAA.
| Clinical Manifestation | Mi-2 (n = 4) | PM-Scl (n = 2) | U1RNP (n = 7) | Ku (n=l) | MJ (n = 16) | p155/140 (n = 14) |
|---|---|---|---|---|---|---|
| Sex F/M | 3/1 | 1/1 | 5/2 | 1/0 | 12/4 | 11/3 |
| Diagnosis | ||||||
| JPM | — | — | — | — | 2 | — |
| JDM | 4 | 1 | 3 | — | 13 | 11 |
| JOS | — | 1 | 4 | 1 | 1 | 3 |
| Dysphagia | 2 | 1 | — | — | 5 | 3 |
| Muscular | ||||||
| Proximal weakness | 4 | 2 | 7 | 1 | 14 | 14 |
| Contractures | — | 1 | 1 | — | 7 | 7 |
| Atrophy | 4 | 1 | — | — | 7 | 2 |
| DM cutaneous signs | 4 | — | 1 | — | 14 | 11 |
| Cutaneous vasculitis | — | 1 | 1 | — | 6 | 8 |
| Calcinosis | 1 | — | — | — | 5 | 5 |
| Interstitial lung disease | — | 1 | 2 | — | 4 | 1 |
| Arthritis | 1 | 1 | 3 | — | 6 | 9 |
| Raynaud phenomenon | — | 2 | 3 | — | 1 | 4 |
JOS: juvenile overlap syndrome; JPM: juvenile polymyositis; JDM: juvenile dermatomyositis.