Table 2.

Renal biopsies from patients with WG.

Patient	Age, yrs	Disease Onset	Clinical Manifestation			BVAS	Laboratory Result			Histopathology	Therapy
Patient	Age, yrs	Disease Onset	ENT	Pulmo	Kidney	BVAS	cANCA	PR-3, U/ml	CRP, mg/ml	Histopathology	Therapy
1	34	2003	+	+	+	24	1:640	279	320	Diffuse necrotizing extracapillary proliferating glomerulonephritis with moderate interstitial nephritis	CYC, GC
2	45	2002	+	−	+	21	1:160	33	18	Focal segmental necrotizing extracapillary proliferating glomerulonephritis with mild interstitial nephritis	CYC, GC
3	54	2002	+	−	+	34	1:160	11	42	Focal segmental necrotizing glomerulonephritis	CYC, GC
4	49	2002	−	+	+	20	1:160	7	59	Focal segmental necrotizing glomerulonephritis with mild interstitial nephritis	CYC, GC
5	29	2002	+	−	+	8	1:320	34	88	Diffuse necrotizing glomerulonephritis with extracapillary proliferation	CYC, GC

ENT: ear, nose, throat; BVAS: Birmingham Vasculitis Activity Score; cANCA: antineutrophil cytoplasmic antibody; PR-3: proteinase-3 antigen; CRP: C-reactive protein; CYC: cyclophosphamide; GC: glucocorticoids.