Relationship between selected disease indicators and serum SP-D. Multiple linear and logistic regression models the mean of the response variable Y as a function of the covariates, where Y = (CRP, ESR, dsDNA, SLICC or SLEDAI) and the covariates are lnSP-D, age, sex, smoking, and Met11Thr polymorphism. The coefficient shown is the estimated regression coefficient for lnSP-D. Anti-dsDNA titer was considered to be positive when > 35 IU/ml.
| Response Variable Y | Partial Regression Coefficient ßlnSP-D (95% CI) | p |
|---|---|---|
| CRP, mg/ml | −4.42 (−17.35; 8.52) | 0.48 |
| ESR, mm/h | −7.18 (−21.39; 7.03) | 0.31 |
| Anti-dsDNA (pos/neg) | 0.55 (−0.33; 1.44) | 0.22 |
| SLICC | −0.53 (−1.56; 0.49) | 0.30 |
| SLEDAI | 0.34 (−0.55; 1.23) | 0.45 |
CRP: C-reactive protein; ESR: erythrocyte sedimentation rate; SLICC: Systemic Lupus International Collaborating Clinics; SLEDAI: SLE Disease Activity Index.