Sensitivities and specificities of office-based rheumatologist (OBR) diagnosis and ACR criteria at inclusion and at 2 years.
| Number Among RA+ (n = 57) | Sensitivity | Number Among RA− (n = 107) | Specificity | |||
|---|---|---|---|---|---|---|
| % | 95% CI | % | 95% CI | |||
| At inclusion | ||||||
| OBR diagnosis* | 53 | 93.0 | 86.4–99.6 | 56 | 52.3 | 42.5–62.1 |
| ACR criteria | 33 | 57.9 | 44.1–70.9 | 80 | 74.8 | 65.5–82.7 |
| Anti-CCP-revised criteria 1** | 37 | 64.9 | 51.1–77.1 | 80 | 74.8 | 65.5–82.7 |
| Anti-CCP-revised criteria 2† | 48 | 84.2 | 72.1–92.5 | 56 | 52.3 | 42.5–62.1 |
| Anti-CCP-revised criteria 3†† | 46 | 80.7 | 68.1–90.0 | 59 | 55.1 | 45.2–64.8 |
| OBR diagnosis/ACR criteria | 32 | 56.1 | 42.4–69.3 | 86 | 80.4 | 71.6–87.4 |
| OBR diagnosis/Anti-CCP-revised criteria 1 | 36 | 63.2 | 49.3–75.6 | 86 | 80.4 | 71.6–87.4 |
| OBR diagnosis/Anti-CCP-revised criteria 2 | 46 | 80.7 | 68.1–90.0 | 77 | 72.0 | 62.5–80.2 |
| OBR diagnosis/Anti-CCP-revised criteria 3 | 44 | 77.2 | 64.2–87.3 | 79 | 73.8 | 64.5–81.9 |
| At 2 years | ||||||
| OBR diagnosis* | 48 | 84.2 | 74.7–93.7 | 91 | 85.0 | 78.3–91.8 |
| ACR criteria | 46 | 80.7 | 70.5–90.0 | 68 | 63.6 | 54.5–72.7 |
| Combination OBR diagnosis/ACR criteria | 44 | 77.2 | 66.3–88.1 | 93 | 86.9 | 80.5–93.3 |
↵* For OBR diagnosis, positive and negative predictive values were estimated. At inclusion, PPV was 51.0% (95% CI 41.4%–60.6%) and NPV was 93.3% (95% CI 87.0%–99.6%). At 2 years, PPV was 75.0% (95% CI 64.4%–85.6%) and NPV was 91.0% (95% CI 85.4%–96.6%).
↵** ACR criteria + anti-CCP;
↵† ACR criteria – nodules + anti-CCP;
↵†† ACR criteria – nodules – erosions + anti-CCP.