Table 3.

C-reactive protein (CRP) basal levels according to the haplotype of CRP gene. CRP values are median (25th percentile, 75th percentile).

HaplotypeCRP Levels mg/lpapb
Ht1[TACGCA]TACGCA (n = 172)0.2 (0.0, 0.4)
− (n = 124)*0.3 (0.1, 0.5)0.006NS
Ht2[TGCGCG]TGCGCG (n = 29)0.4 (0.3, 0.5)
− (n = 267)*0.3 (0.2, 1.0)NSNS
Ht3[CAAGCG]CAAGCG (n = 43)0.4 (0.2, 0.5)
− (n = 253)*0.2 (0.0, 0.4)NSNS
Ht4[TATGTG]TATGTG (n = 23)0.3 (0.2, 0.5)
− (n = 273)*0.2 (0.0, 0.5)0.035NS
Ht5[TACCCA]TACCCA (n = 12)0.1 (0.0, 0.3)
− (n = 284)*0.3 (0.1, 0.5)NSNS
Ht6[TACGCG]TACGCG (n = 6)0.8 (0.2, 1.2)
− (n = 290)*0.3 (0.0, 0.5)NSNS
Ht7[TACGTG]TACGTG (n = 4)0.2 (0.0, 0.4)
− (n = 292)*0.3 (0.1, 0.5)NSNS
  • a Logistic regression analysis to control for disease duration as a covariable.

  • b Bonferroni adjustment for multiple comparisons. NS: not significant.

  • * SLE patients who did not have haplotype.