Table 2.

C-reactive protein (CRP) basal levels according to the SNP genotype in SLE. CRP values are median (25th percentile, 75th percentile).

SNPGenotypeCRP levels (mg/l)papb
−861 T>C
  TT (n = 105)0.2 (0.0, 0.4)
  CT, CC (n = 43)0.4 (0.2, 0.5)NSNS
−821 A>G
  AA (n = 122)0.2 (0.0, 0.4)
  AG, GG (n = 26)0.4 (0.3, 0.6)0.042NS
−390 C>A or T
  CC (n = 78)0.2 (0.0, 0.4)
  CT, AC, AA, AT, or TT (n = 70)0.3 (0.2, 0.5)0.0230.03
839 G>C
  GG (n = 136)0.3 (0.1,0.5)
  CG, CC (n = 12)0.1 (0.0, 0.3)NSNS
1185 C>T
  CC (n = 122)0.2 (0.0, 0.5)
  CT, TT (n = 26)0.3 (0.2, 0.5)NSNS
2043 A>G
  AA (n = 60)0.2 (0.0, 0.4)
  AG, GG (n = 88)0.3 (0.2, 0.5)0.050.024

  • ↵a Logistic regression analysis to control for disease duration as a covariable.

  • ↵b Bonferroni adjustment for multiple comparisons. NS: not significant.