Environmental factors associated with SSc.
| 1 Silica, silicon, and silicones | |
| Silica dust | Gold and coal miners |
| Stone masons | |
| Abrasive powder work | |
| Breast Implants | Silicone |
| Paraffin | |
| 2 Inorganic compounds | |
| Aromatic hydrocarbons | Toluene |
| Benzene | |
| Xylene | |
| Aromatic blends (diesel, etc.) | |
| Aliphatic hydrocarbons | |
| Chlorated | Vinyl chloride |
| Trichloroethylene | |
| Perchloroethylene | |
| Naphta-n-hexane | |
| Non chlorated | |
| Epoxy resins | |
| Biogenic amines | |
| Urea-formaldehyde foam | |
| 3 Drugs | Bleomycin |
| Carbidopa | |
| L-5-hydroxytryptophan | |
| Pentazocine | |
| Cocaine | |
| Appetite suppressants | |
| Diethylpropion | |
| Fenfluramine chlorohydrate | |
| 4 Rapeseed oil | |
| 5 L-tryptophan | |