Minimally important difference for the pain, fatigue, and sleep visual analog scale and Health Assessment Questionnaire-Disability Index (HAQ-DI) in the single site London, ON SLE Cohort (n = 202).
| Patient-rated Overall Status | Pain Change Mean (SD) [95% CI]* | Fatigue Change Mean (SD) [95% CI]* | Sleep Change Mean (SD) [95% CI]* | HAQ-DI Change Mean (SD) [95% CI]** |
|---|---|---|---|---|
| Much Better | −18.7 (32.5) [−37.5 to 0.0] | −21.4 (30.6) [−39.1 to−3.8] | −25.4 (34.3) [−45.2 to −5.6] | −0.28 (0.43) [−0.52 to −0.03] |
| Better | −15.8 (16.0) [−21.5 to −10.1] | −13.9 (30.6) [−24.8 to −3.0] | −8.6 (24.6) [−17.3 to 0.1] | −0.08 (0.32) [−0.20 to 0.03] |
| The same | −3.7 (22.8) [−8.2 to 0.8] | −0.1 (28.3) [−5.7 to 5.5] | −5.5 (27.9) [−11.1 to 0.0] | −0.02 (0.29) [−0.08 to 0.04] |
| Worse | 8.5 (21.5) [2.4 to 14.6] | 9.1 (18.0) [4.0 to 14.2] | 7.6 (24.6) [0.6 to 14.6] | 0.14 (0.40) [0.03 to 0.26] |
| Much worse | 20.8 (11.7) [6.3 to 35.3] | 18.2 (38.1) [−29.1 to 65.5] | 14.0 (12.9) [−2.1 to 30.1] | 0.46 (0.69) [−0.40 to 1.31] |
SD: standard deviation; CI: confidence interval.
↵* Measured on a scale from 0–100 mm where 100 would indicate a worse outcome. The change is the score from the most recent visit minus the previous visit so that a negative score indicates an improvement in the outcome.
↵** The HAQ-DI is scored from 0–3, where 0 indicates no difficulty with activities of daily living (ADL). The HAQ-DI change score is that of the most recent visit minus the previous visit so that a negative score indicates less difficulty with ADL (an improvement).