Table 9.

Results of interaction test for IL9R (rs3093457) in subgroups of the combined set 1 & 2 & 3.

MaleFemale
No. of cases55382
  Minor allele GRR (95% CI)3.75 (1.4–10.2)1.26 (0.8–1.9)
  Ratio of GRR (95% CI)2.98 (1.01–8.79)
  p0.048
a-CCP+a-CCP−
No. of cases20972
  Minor allele GRR (95% CI)1.76 (1.0–3)1.05 (0.3–3.1)
  Ratio of GRR (95% CI)0.6 (0.16–2.17)
  p0.216
  • GRR: genetic relative risk. Male and female subgroups: family trios with male or female patients; a-CCP+ and a-CCP− subgroups: anti-CCP-positive and negative subgroups, i.e., family trios with anti-CCP-positive or negative patients.