Influence of disease-related factors on areal bone mineral density (BMDa) at the lumbar spine and total hip. Results are expressed as ß-coefficient (95% CI) adjusted for age and sex.
| Lumbar Spine BMDa (g/cm2) | Total Hip BMDa (g/cm2) | |
|---|---|---|
| Weight, kg | 0.005 (0.003, 0.007)* | 0.006 (0.003, 0.009)* |
| Height, cm | 0.007 (0.004, 0.011)* | 0.012 (0.005, 0.019)* |
| Age at scan, yrs | 0.004 (0.001, 0.007)* | 0.000 (−0.006, 0.006) |
| Sex (F vs M) | −0.046 (−0.136, 0.045) | −0.040 (−0.195, 0.114) |
| Disease duration, yrs | −0.005 (−0.011, 0.001) | −0.004 (−0.015, 0.006) |
| HAQ score (0–3) | −0.099 (−0.148, − 0.051)* | −0.122 (−0.217, −0.026)* |
| ESR, mm/h | 0.000 (−0.002, 0.003) | 0.002 (−0.004, 0.007) |
| ESR, mm/h | ||
| < 20 | Referent | Referent |
| ≥ 20 | −0.007 (−0.110, 0.097) | 0.057 (−0.142, 0.255) |
| CRP, mg/l | −0.001 (−0.004, 0.001) | −0.001 (−0.005, 0.003) |
| RF-positive (yes vs no) | 0.023 (−0.058, 0.103) | 0.057 (−0.065, 0.178) |
| Disease subtype | ||
| Oligoarticular | Referent | Referent |
| Systemic | −0.108 (−0.222, 0.007) | −0.180 (−0.382, 0.022) |
| Extended oligoarticular | −0.034 (−0.167, 0.098) | −0.280 (−0.496, −0.064)* |
| Polyarticular RF-positive | −0.101 (−0.205, 0.003) | −0.098 (−0.266, 0.070) |
| Polyarticular RF-negative | −0.090 (−0.190, 0.009) | −0.184 (−0.343, − 0.025)* |
| Psoriasis | 0.036 (−0.116, 0.188) | 0.074 (−0.154, 0.302) |
| Enthesitis-related | 0.212 (0.044, 0.379)* | 0.053 (−0.226, 0.333) |
| Other | −0.062 (−0.287, 0.163) | 0.072 (−0.267, 0.411) |
| Oral corticosteroids (yes vs no) | −0.143 (−0.211, −0.075)* | −0.136 (−0.248, −0.024)* |
| Methotrexate (yes vs no) | −0.071 (−0.154, 0.013) | 0.015 (−0.112, 0.143) |
| Large-joint replacement (yes vs no) | −0.101 (−0.188, −0.013)* | −0.194 (−0.343, −0.046)* |
↵* p < 0.05. RF: rheumatoid factor; HAQ: Health Assessment Questionnaire; ESR: erythrocyte sedimentation rate; CRP: C-reactive protein.